Serotonin Signaling Trough Prelimbic 5-HT1A Receptors Modulates CSDS-Induced Behavioral Changes in Adult Female Voles
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چکیده
منابع مشابه
Interaction between serotonin 5-HT1A receptors and beta-endorphins modulates antidepressant response.
UNLABELLED Interactions between serotonergic and the endogenous opioid systems have been suggested to be involved in the etiopathogenesis of depression and in the mechanism of action of antidepressants. Activation of serotonin 5-HT1A receptors has been shown to increase plasma beta-endorphin (beta-END) levels in animal studies and in healthy humans. OBJECTIVES To assess interaction abnormalit...
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Alterations of the serotonergic system in the prefrontal cortex (PFC) are implicated in psychiatric disorders such as schizophrenia and depression. Although abnormal synchronous activity is observed in the PFC of these patients, little is known about the role of serotonin (5-HT) in cortical synchrony. We found that 5-HT, released by electrical stimulation of the dorsal raphe nucleus (DRN) in an...
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s | 49 maze, and motor coordination by rotarod after caffeine administration for 7 days. Water maze performance by measuring the latency to reach the platform was significantly better in the group of mice receiving moderate dose of caffeine (30.4 ± 7.3 s) compared to the control group latency (63.6 ± 9.4 s, ANOVA test, p˂ 0.05) and the high dose group latency (76.9 ± 8.5 s, ANOVA test, p˂ 0.05)...
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Common chemotherapeutic agents such as vincristine often cause neuropathic pain during cancer treatment in patients. Such neuropathic pain is refractory to common analgesics and represents a challenging clinical issue. Angelicae dahuricae radix is an old traditional Chinese medicine with demonstrated analgesic efficacy in humans. However, the active component(s) that attribute to the analgesic ...
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ژورنال
عنوان ژورنال: International Journal of Neuropsychopharmacology
سال: 2018
ISSN: 1461-1457,1469-5111
DOI: 10.1093/ijnp/pyy093